Description

(S)-(+)-1-Methoxy-2-Propanol CAS NO 116422-39-0 is a high-purity, single-enantiomer chiral alcohol derivative of propylene glycol methyl ether. This optically active compound is valued for its role as a versatile chiral building block and solvent in advanced synthetic chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high stereochemical purity for developing active pharmaceutical ingredients (APIs), chiral catalysts, and fine chemicals.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material or resolving agent for the production of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst and Ligand Preparation: Used in the synthesis of chiral ligands and organocatalysts for stereoselective reactions.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where biological activity is stereospecific.
• Specialty Solvent for Chiral Chemistry: Serves as a polar, aprotic solvent medium for reactions requiring chiral induction or enantioselective crystallization.
• Fine Chemical and Flavor/Fragrance Synthesis: A building block for creating enantiomerically enriched flavors, fragrances, and other high-value aroma chemicals.
• Academic and R&D Laboratories: A critical reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(S)-(+)-1-Methoxy-2-Propanol
CAS No.	116422-39-0
Molecular Formula	C4H10O2
Molecular Weight	90.12 g/mol
Synonyms	(S)-(+)-1-Methoxy-2-propanol; (S)-1-Methoxy-2-propanol; (S)-(+)-Propylene glycol monomethyl ether; (S)-PGME; (S)-1-Methoxypropan-2-ol; (S)-2-Methoxy-1-methylethanol; (S)-Methyl propylene glycol; (S)-Methoxyisopropanol
EINECS	Contact for details

Quality Control

Our (S)-(+)-1-Methoxy-2-Propanol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral chromatography, NMR, and GC/HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess (ee), and impurity profile is provided with every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize moisture absorption and evaporation.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to standard
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]20/D	+10.0° to +12.0° (c=1, neat)
Water Content (KF)	≤ 0.5%
Residue on Evaporation	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.