Description

1-Hydroxyisoquinoline-8-Carboxylic Acid is a versatile heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure makes it a valuable precursor for developing complex molecules with specific electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting enzymes and receptors where the isoquinoline scaffold is relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require complex heterocyclic cores.
• Ligand Synthesis: Serves as a starting material for creating chelating ligands in coordination chemistry and catalysis.
• Material Science: Building block for organic semiconductors, dyes, and photoactive materials due to its conjugated system.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying biological pathways.
• Academic & Industrial R&D: Fundamental research compound for methodological development and exploring new chemical spaces in organic chemistry.

Basic Information

Product Name	1-Hydroxyisoquinoline-8-Carboxylic Acid
CAS No.	116409-31-5
Molecular Formula	C10H7NO3
Molecular Weight	189.17 g/mol
Synonyms	8-Carboxy-1-hydroxyisoquinoline; 1-Hydroxy-8-isoquinolinecarboxylic Acid; 1-Hydroxyisoquinoline-8-carboxylic acid; Isoquinoline-8-carboxylic acid, 1-hydroxy-; 1-Hydroxy-8-carboxyisoquinoline; 8-Isoquinolinecarboxylic acid, 1-hydroxy-
EINECS	Contact for details

Quality Control

Our 1-Hydroxyisoquinoline-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.