Description

2-Chloro-3-Bromo-5-Nitrotoluene is a halogenated nitrotoluene derivative, a versatile and high-purity organic intermediate essential for advanced chemical synthesis. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the nitro and halogen groups contribute to biological activity.
• Dye and Pigment Manufacturing: Serves as a building block for synthesizing specialized azo dyes and organic pigments.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers or nonlinear optical (NLO) materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) due to the presence of reactive bromo and chloro substituents.
• Ligand and Catalyst Development: Useful for constructing sophisticated ligand systems in coordination chemistry and catalysis.

Basic Information

Product Name	2-Chloro-3-Bromo-5-Nitrotoluene
CAS No.	116277-60-2
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	1-Chloro-2-bromo-4-methyl-5-nitrobenzene; Toluene, 2-chloro-3-bromo-5-nitro-; 3-Bromo-2-chloro-5-nitrotoluene; 2-Chloro-3-bromo-5-methylnitrobenzene; 5-Nitro-2-chloro-3-bromotoluene; 2-Bromo-3-chloro-5-nitrotoluene (isomer); Halogenated Nitrotoluene Derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Bromo-5-Nitrotoluene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP environments and research requiring the highest material integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.