Description

Hesperetin Benzyl Ether is a chemically modified derivative of the natural citrus flavonoid hesperetin. This compound is valued for its enhanced stability and lipophilicity compared to its parent molecule, making it a versatile intermediate for advanced research and development. It is primarily utilized in the pharmaceutical, nutraceutical, and cosmetic industries for the synthesis of novel bioactive compounds and as a reference standard. The product is supplied under the CAS registry number 116222-56-1.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates targeting inflammation, metabolic disorders, and oxidative stress.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of flavonoid-based products.
• Nutraceutical Research: Investigated for its potential bioactivity and improved bioavailability in advanced dietary supplement formulations.
• Cosmetic Actives Development: Serves as a precursor for creating stable, skin-beneficial ingredients with antioxidant and anti-aging properties.
• Biochemical Research: Employed in studies to understand structure-activity relationships (SAR) of flavonoid derivatives.
• Fine Chemical Synthesis: A specialized intermediate for custom synthesis and contract manufacturing of high-value chemical entities.

Basic Information

Product Name	Hesperetin Benzyl Ether
CAS No.	116222-56-1
Molecular Formula	C23H20O6
Molecular Weight	392.40 g/mol
Synonyms	Hesperetin 7-Benzyl Ether; 5,7-Dihydroxy-3'-methoxy-4'-benzyloxyflavanone; 3',5,7-Trihydroxy-4'-methoxyflavanone 7-benzyl ether; 4'-Methoxy-3',5,7-trihydroxyflavanone 7-benzyl ether; Hesperetin 7-O-benzyl ether; Benzyl hesperetin ether; 7-Benzyloxy-5-hydroxy-3'-methoxy-4'-hydroxyflavanone (common misnomer); 7-O-Benzylhesperetin
EINECS	Contact for details

Quality Control

Our Hesperetin Benzyl Ether is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.