Description

4-Bromo-2-Mercaptobenzoic Acid is a versatile and high-value brominated benzoic acid derivative featuring both a carboxylic acid and a thiol (mercapto) functional group. This unique bifunctional structure makes it a critical pharmaceutical intermediate and a valuable building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a bromo-substituted aromatic scaffold with orthogonal reactivity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and other crop protection agents.
• Ligand and Catalyst Development: The thiol and carboxylic acid groups allow it to act as a chelating ligand for metal catalysts in various organic transformations.
• Material Science: Employed in the synthesis of functionalized polymers, liquid crystals, and advanced organic materials.
• Chemical Research: A valuable reagent for academic and industrial research in medicinal chemistry, process chemistry, and methodology development.
• Custom Synthesis: Used as a starting material for the contract manufacturing of complex, bespoke organic molecules.

Basic Information

Product Name	4-Bromo-2-Mercaptobenzoic Acid
CAS No.	116209-30-4
Molecular Formula	C7H5BrO2S
Molecular Weight	233.08 g/mol
Synonyms	2-Mercapto-4-bromobenzoic Acid; 4-Bromo-2-sulfanylbenzoic Acid; Benzoic acid, 4-bromo-2-mercapto-; 4-Bromothiosalicylic Acid; 2-Sulfanyl-4-bromobenzoic Acid; 4-Bromo-2-thiobenzoic Acid; 4-Bromo-2-mercaptobenzoic acid (primary name)
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for 4-Bromo-2-Mercaptobenzoic Acid typically meets a purity specification of ≥97% (by HPLC), suitable for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We can also support development projects requiring custom purity grades or specific impurity thresholds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation, especially after the container has been opened. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.