Description

(+)-4-Propyl-4H-Naphth[2,3-B]-1,4-Oxazin-9-Ol CAS NO 116198-47-1 is a chiral, high-purity organic compound belonging to the naphthoxazine class, characterized by its specific stereochemistry and functional groups. This compound is valued for its role as a key synthetic intermediate or building block in advanced organic synthesis, particularly in the development of pharmaceuticals and specialty chemicals. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in creating novel active ingredients or complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets or receptor modulators.
• Asymmetric Synthesis: Utilized in catalytic or stoichiometric asymmetric reactions to introduce stereochemical complexity into target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs due to its defined stereochemistry and functional handle.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals, dyes, or advanced materials requiring a specific naphthoxazine core.
• Academic & Industrial R&D: Used in methodological development and exploratory chemistry within academic and corporate research settings.

Basic Information

Product Name	(+)-4-Propyl-4H-Naphth[2,3-B]-1,4-Oxazin-9-Ol
CAS No.	116198-47-1
Molecular Formula	C₁₇H₁₇NO₂
Molecular Weight	267.32 g/mol
Synonyms	(+)-4-Propyl-4H-naphtho[2,3-b][1,4]oxazin-9-ol; (4R)-4-Propyl-4H-naphth[2,3-b][1,4]oxazin-9-ol; 9-Hydroxy-4-propyl-4H-naphth[2,3-b]-1,4-oxazine; (R)-4-Propyl-4H-naphth[2,3-b][1,4]oxazin-9-ol; 4H-Naphth[2,3-b]-1,4-oxazin-9-ol, 4-propyl-, (4R)-; (+)-4-Propyl-4H-naphth[2,3-b]-1,4-oxazin-9-ol
EINECS	Contact for details

Quality Control

Our (+)-4-Propyl-4H-Naphth[2,3-B]-1,4-Oxazin-9-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.