Description

(3S)-(+)-3-Aminopyrrolidine Dihydrochloride CAS NO 116183-83-6 is a high-purity, chiral building block essential for modern pharmaceutical synthesis. Its value lies in its role as a key intermediate for creating complex, biologically active molecules with defined stereochemistry. This compound is critically needed by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in areas like protease inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, especially protease inhibitors and other targeted therapies.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Peptidomimetics Research: Serves as a constrained scaffold in the design and development of peptide analogs with improved metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of molecular tools for studying enzyme mechanisms and biological pathways.
• Agrochemical Development: Potential use as an intermediate in the synthesis of advanced, chiral crop protection agents.

Basic Information

Product Name	(3S)-(+)-3-Aminopyrrolidine Dihydrochloride
CAS No.	116183-83-6
Molecular Formula	C4H10N2·2HCl
Molecular Weight	167.06 g/mol
Synonyms	(3S)-3-Aminopyrrolidine Dihydrochloride; (+)-(3S)-3-Aminopyrrolidine Dihydrochloride; (S)-(+)-3-Aminopyrrolidine Dihydrochloride; (S)-3-Aminopyrrolidine Dihydrochloride; (S)-3-Pyrrolidinamine Dihydrochloride; (3S)-3-Pyrrolidinamine Dihydrochloride; (S)-(+)-3-Pyrrolidinamine Dihydrochloride; 3-Aminopyrrolidine Dihydrochloride (S-enantiomer)
EINECS	Contact for details

Quality Control

Our (3S)-(+)-3-Aminopyrrolidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. A detailed Certificate of Analysis (COA) providing full specifications and test results is available for every lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.