Description

Cis(1-Aminocyclobutane-1,3-Dicarboxylic Acid) Hydrochloride is a high-purity, cyclobutane-based amino acid derivative, primarily utilized as a key intermediate in advanced pharmaceutical research and development. This compound is valued for its rigid, constrained structure, which is instrumental in the design and synthesis of novel bioactive molecules and drug candidates. It is essential for medicinal chemists and researchers in the pharmaceutical and biotechnology sectors focused on neuroscience, metabolic disorders, and oncology.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop compounds with enhanced potency and selectivity.
• Biochemical Tool Compound: Serves as a reference standard or a precursor in the development of enzyme inhibitors or receptor modulators.
• Peptidomimetics: Incorporated into peptide analogs to confer conformational rigidity and improve metabolic stability.
• Academic & Institutional R&D: Employed in university and research institute laboratories for fundamental chemical and biological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	Cis(1-Aminocyclobutane-1,3-Dicarboxylic Acid) Hydrochloride
CAS No.	116129-08-9
Molecular Formula	C7H10ClNO4
Molecular Weight	207.61 g/mol
Synonyms	(1R,3S)-1-Amino-3-carboxycyclobutane-1-carboxylic acid hydrochloride; (1S,3R)-1-Amino-3-carboxycyclobutane-1-carboxylic acid hydrochloride; cis-1-Amino-1,3-cyclobutanedicarboxylic acid hydrochloride; cis-ACBD hydrochloride; cis-ACBD-HCl; (1-Aminocyclobutane-1,3-dicarboxylic acid) hydrochloride, cis-; 1-Amino-1,3-cyclobutanedicarboxylic acid hydrochloride (cis isomer)
EINECS	Contact for details

Quality Control

Our Cis(1-Aminocyclobutane-1,3-Dicarboxylic Acid) Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.