Description

Diacetato[(R)-(+)-2,2'-Bis(Di-p-Tolylphosphino)-1,1'-Binaphthyl]Ruthenium(II) is a highly specialized, chiral ruthenium complex that serves as a premier asymmetric hydrogenation catalyst. Its value lies in enabling the efficient and selective synthesis of single-enantiomer intermediates, which are critical for producing optically pure pharmaceuticals and fine chemicals. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance, enantioselective catalysts.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Pharmaceutical Manufacturing: Production of chiral active pharmaceutical ingredients (APIs) for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
• Agrochemical Synthesis: Creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Synthesis of high-value chiral building blocks, flavors, and fragrances.
• Academic & Industrial R&D: A key reagent for methodological development in organic synthesis and catalysis research.
• Process Optimization: Scaling up laboratory asymmetric transformations to commercial manufacturing processes.

Basic Information

Product Name	Diacetato[(R)-(+)-2,2'-Bis(Di-p-Tolylphosphino)-1,1'-Binaphthyl]Ruthenium(II)
CAS No.	116128-29-1
Molecular Formula	C58H52O4P2Ru
Molecular Weight	966.04 g/mol
Synonyms	(R)-Ru(OAc)2(Tol-BINAP); (R)-Diacetatobis[di-p-tolylphosphino]-1,1'-binaphthylruthenium(II); (R)-Ru(OCOCH3)2(TolBINAP); Ru(Tol-BINAP)(OAc)2; (R)-TolBINAP-Ru diacetate; (R)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl ruthenium(II) diacetate; (R)-Ru(TolBINAP)(OAc)2; Ruthenium(II) acetate complex with (R)-(+)-4,4',5,5'-tetrahydro-4,4,5,5'-tetramethyl-2,2'-bis(di-p-tolylphosphino)-1,1'-binaphthyl
EINECS	Contact for details

Quality Control

Every batch of our Diacetato[(R)-(+)-2,2'-Bis(Di-p-Tolylphosphino)-1,1'-Binaphthyl]Ruthenium(II) is manufactured and tested under strict quality management systems to ensure exceptional purity, catalytic activity, and enantiomeric integrity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as Ru content, chiral purity, and solvent residues. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will degrade its catalytic performance.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Assay (Ru content)	≥ 10.5 %
Chiral Purity (HPLC)	≥ 99.0 % (R)-isomer
Solvent Residues (GC)	Meet ICH guidelines
Heavy Metals (ICP-MS)	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.