Description

2'-Chloroflavone is a synthetically derived flavonoid derivative, characterized by the strategic chlorination at the 2' position of its flavone backbone. This specific structural modification is of significant interest as it can dramatically alter the compound's biological activity, electronic properties, and binding affinity compared to its parent molecule. It serves as a critical building block and reference standard for researchers and developers in advanced chemical synthesis. This compound is primarily utilized by professionals in pharmaceutical R&D, agrochemical discovery, and academic research for investigating structure-activity relationships and developing novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates targeting various therapeutic areas.
• Biochemical Research: Used as a reference standard and probe compound in studies of enzyme inhibition, receptor binding, and cellular signaling pathways.
• Agrochemical Development: Serves as a structural scaffold for creating new active ingredients in crop protection products.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the chlorinated flavone moiety into larger, more complex molecular architectures.
• Material Science Research: Investigated for its potential photophysical properties in the development of organic electronic materials.

Basic Information

Product Name	2'-Chloroflavone
CAS No.	116115-48-1
Molecular Formula	C15H9ClO2
Molecular Weight	256.68 g/mol
Synonyms	2'-Chloro-2-phenyl-4H-chromen-4-one; 2'-Chloro-2-phenyl-4H-1-benzopyran-4-one; 2'-Chloroflavone; Flavone, 2'-chloro-; 2-(2-Chlorophenyl)-4H-chromen-4-one
EINECS	Contact for details

Quality Control

Our 2'-Chloroflavone is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity determination, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications. For cGMP or other specific regulatory grade requirements, please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.