Description

Nojirimycin 6-Phosphate is a chemically modified derivative of the natural product nojirimycin, a potent glycosidase inhibitor. This phosphorylated analog is a critical biochemical tool and research intermediate, offering enhanced properties for studying carbohydrate metabolism and enzyme inhibition. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for drug discovery programs targeting metabolic disorders and infectious diseases.

Application

• Biochemical Research: As a key intermediate and reference standard in the study of glycosidase and glycosyltransferase enzymes.
• Pharmaceutical Development: Serves as a precursor or pharmacophore in the synthesis of novel therapeutic agents for diabetes, viral infections (e.g., HIV, influenza), and lysosomal storage diseases.
• Enzyme Inhibition Studies: Used to investigate the mechanisms of carbohydrate-processing enzymes and to develop high-throughput screening assays.
• Academic Research: Employed in universities and research institutes for fundamental studies in glycobiology and medicinal chemistry.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of specialized diagnostic kits for enzyme activity detection.

Basic Information

Product Name	Nojirimycin 6-Phosphate
CAS No.	116026-31-4
Molecular Formula	C6H14NO9P
Molecular Weight	275.15 g/mol
Synonyms	6-Phosphonooxymethyl-5-amino-5-deoxy-D-glucopyranose; 5-Amino-5-deoxy-D-glucopyranose 6-(dihydrogen phosphate); Nojirimycin 6-O-Phosphate; 5-Amino-5-deoxy-D-glucose 6-phosphate; D-Nojirimycin 6-Phosphate; 6-Phosphonooxymethyl-5-imino-5-deoxy-D-glucitol
EINECS	Contact for details

Quality Control

Our Nojirimycin 6-Phosphate is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.