Description

Sucrose 4,6-Methyl Orthoester is a specialized carbohydrate derivative where a methyl orthoester group bridges the 4 and 6 positions of the sucrose molecule. This unique structure makes it a valuable protected intermediate and chiral building block for advanced organic synthesis. It is primarily sought after by researchers and manufacturers in the pharmaceutical and fine chemical industries for the development of novel compounds, including complex carbohydrates, nucleoside analogs, and prodrugs.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex nucleoside analogs and antiviral/anticancer drug candidates.
• Carbohydrate Chemistry: Serves as a protected sucrose derivative for regioselective glycosylation and oligosaccharide assembly.
• Prodrug Development: Utilized to create masked or targeted prodrug forms of active pharmaceutical ingredients (APIs) to improve bioavailability or stability.
• Fine Chemical Synthesis: Acts as a versatile building block for synthesizing specialty surfactants, ligands, and chiral auxiliaries.
• Bioconjugation: Potential use in linking biomolecules (e.g., peptides, proteins) to sugars for diagnostic or therapeutic applications.
• Research & Development: Essential tool compound in academic and industrial R&D for exploring new synthetic methodologies and bioactive molecules.

Basic Information

Item	Detail
Product Name	Sucrose 4,6-Methyl Orthoester
CAS No.	116015-72-6
Molecular Formula	C13H22O11
Molecular Weight	354.31 g/mol
Synonyms	4,6-O-Methylidene-α-D-glucopyranosyl β-D-fructofuranoside; Sucrose 4,6-O-methylidene acetal; 4,6-O-Methylidene sucrose; Sucrose 4,6-acetal; 1,3,4,6-Tetra-O-acetyl-2-O-trichloroacetyl-α-D-glucopyranosyl 1,3,4,6-tetra-O-acetyl-2-O-trichloroacetyl-β-D-fructofuranoside (related protected form); Sucrose cyclic 4,6-(methyl orthoester)
EINECS	Contact for details

Quality Control

Our Sucrose 4,6-Methyl Orthoester is produced under stringent conditions to ensure high chemical purity and batch-to-batch consistency, suitable for demanding synthetic applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and relevant physicochemical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment to prevent hydrolysis of the orthoester group.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.