Description

4-(2,4-Dioxo-1,4-dihydroquinazolin-3(2H)-yl)butanoic acid is a high-purity, synthetically derived quinazoline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacophore and versatile synthetic intermediate for constructing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers focused on oncology, neurology, and enzyme inhibition therapeutics.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and mechanism-of-action studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• API Development: Employed in the research phase for developing new Active Pharmaceutical Ingredients (APIs) with potential anticancer or neuroprotective properties.
• Custom Synthesis: A starting material for contract manufacturing and custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4-(2,4-Dioxo-1,4-dihydroquinazolin-3(2H)-yl)butanoic Acid
CAS No.	115948-87-3
Molecular Formula	C₁₂H₁₂N₂O₄
Molecular Weight	248.24 g/mol
Synonyms	3-(3-Carboxypropyl)quinazoline-2,4(1H,3H)-dione; 4-(2,4-Dioxo-3,4-dihydro-1H-quinazolin-3-yl)butanoic acid; 4-(2,4-Dioxo-1,4-dihydro-2H-quinazolin-3-yl)butyric acid; 3-(4-Carboxybutyl)quinazoline-2,4(1H,3H)-dione; Quinazoline-2,4(1H,3H)-dione, 3-(3-carboxypropyl)-; Butanoic acid, 4-(2,4-dioxo-1,4-dihydro-3H-quinazolin-3-yl)-
EINECS	Contact for details

Quality Control

Every batch of our 4-(2,4-Dioxo-1,4-dihydroquinazolin-3(2H)-yl)butanoic acid is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and research requirements. Certificates of Analysis (COA) with detailed HPLC/GC and NMR results are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.