Description

2-[4-(Trifluoromethyl)Phenyl]Thiophene is a high-value fluorinated aromatic heterocyclic compound, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethylphenyl group, making it indispensable for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, crop protection, and functional material synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and metabolic stability.
• Organic Electronic Materials: Serves as a precursor for conjugated molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the design of specialized ligands for transition metal catalysis, enabling more efficient and selective synthetic transformations.
• Fluorinated Liquid Crystal Research: Acts as a core component in the development of fluorinated mesogens for advanced display technologies.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science exploration, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-[4-(Trifluoromethyl)Phenyl]Thiophene
CAS No.	115933-15-8
Molecular Formula	C11H7F3S
Molecular Weight	228.23 g/mol
Synonyms	2-[4-(Trifluoromethyl)phenyl]thiophene; 4-(2-Thienyl)benzotrifluoride; 2-(4-Trifluoromethylphenyl)thiophene; 2-(α,α,α-Trifluoro-p-tolyl)thiophene; 1-Trifluoromethyl-4-(2-thienyl)benzene; p-(2-Thienyl)benzotrifluoride; 4-(Thiophen-2-yl)benzotrifluoride
EINECS	Contact for details

Quality Control

Our 2-[4-(Trifluoromethyl)Phenyl]Thiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.