Description

3-Chloro-4-Trifluoromethyl-Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid building block distinguished by its unique halogenated and fluorinated structure. This compound is critical for synthesizing advanced molecules where the trifluoromethyl and chloro substituents impart desirable properties such as enhanced lipophilicity, metabolic stability, and biological activity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Polymer & Material Science: Incorporated as a monomer or modifier to create specialty polymers with specific chemical resistance or surface properties.
• Organic Synthesis & Catalysis: Employed as a versatile building block in cross-coupling reactions and for introducing fluorinated aromatic systems into complex molecules.
• Research & Development: Essential for academic and industrial R&D in exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-Chloro-4-Trifluoromethyl-Benzoic Acid
CAS No.	115754-20-6
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	3-Chloro-4-(trifluoromethyl)benzoic acid; 4-Trifluoromethyl-3-chlorobenzoic acid; Benzoic acid, 3-chloro-4-(trifluoromethyl)-; 3-Chloro-alpha,alpha,α-trifluoro-p-toluic acid; 3-Chloro-4-trifluoromethylbenzoic acid; 3-Chloro-4-(trifluoromethyl)benzoic acid; 115754-20-6; 3-Chloro-4-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-Trifluoromethyl-Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.