Description

1-Amino-1-(Hydroxymethyl)Cyclopropane Hydrochloride is a versatile and highly functionalized cyclopropane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique strained-ring structure combined with both amino and hydroxymethyl functionalities makes it invaluable for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its cyclopropane scaffold.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioisosteres: The aminomethylcyclopropane moiety is employed to create conformationally restricted analogs of amino acids and peptides.
• Material Science Research: Investigated as a monomer or cross-linking agent for specialty polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	1-Amino-1-(Hydroxymethyl)Cyclopropane Hydrochloride
CAS No.	115652-52-3
Molecular Formula	C5H10ClNO
Molecular Weight	135.59 g/mol
Synonyms	(1-Aminocyclopropyl)methanol hydrochloride; 1-(Aminomethyl)cyclopropanol hydrochloride; 1-Amino-1-(hydroxymethyl)cyclopropane HCl; Aminomethylcyclopropanol hydrochloride; (1-Hydroxymethylcyclopropyl)amine hydrochloride; Cyclopropanemethanol, 1-amino-, hydrochloride; 1-Cyclopropyl-1-amino-methanol hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Amino-1-(Hydroxymethyl)Cyclopropane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.