Description

(1R,2R)-trans-2-Amino-1,2,3,4-Tetrahydro-1-Naphthol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. Its defined stereochemistry and functional groups make it a critical precursor for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material synthesis sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular systems.
• Asymmetric Catalyst Ligand Precursor: Used in the development of chiral ligands for catalytic asymmetric synthesis.
• Agrochemical Research: Serves as a building block for novel, optically active pesticides and herbicides.
• Fine Chemical Synthesis: Employed in the multistep synthesis of specialty chemicals and advanced materials.
• Academic & R&D: A valuable reagent for methodological development in organic and medicinal chemistry research.

Basic Information

Product Name	(1R,2R)-trans-2-Amino-1,2,3,4-Tetrahydro-1-Naphthol Hydrochloride
CAS No.	115563-64-9
Molecular Formula	C₁₀H₁₄ClNO
Molecular Weight	199.68 g/mol
Synonyms	(1R,2R)-2-Amino-1,2,3,4-tetrahydro-1-naphthalenol hydrochloride; (1R,2R)-1-Amino-2-hydroxy-1,2,3,4-tetrahydronaphthalene hydrochloride; trans-2-Amino-1,2,3,4-tetrahydro-1-naphthol hydrochloride (1R,2R)-; (1R,2R)-1,2,3,4-Tetrahydro-2-amino-1-naphthol hydrochloride; (1R,2R)-1,2,3,4-Tetrahydro-1-hydroxy-2-naphthylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,2R)-trans-2-Amino-1,2,3,4-Tetrahydro-1-Naphthol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.