Description

(2S)-2-Methylpyrrolidine-2-Methanol Hydrochloride is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its defined stereochemistry and functionalized pyrrolidine core, which is crucial for constructing complex molecules with specific biological activity. This compound is primarily needed by pharmaceutical research and development organizations, agrochemical companies, and advanced material scientists for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Agrochemical Synthesis: Serves as a building block for creating advanced, stereospecific pesticides and herbicides.
• Medicinal Chemistry Research: Employed in hit-to-lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	(2S)-2-Methylpyrrolidine-2-Methanol Hydrochloride
CAS No.	115512-58-8
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	(2S)-2-(Hydroxymethyl)-2-methylpyrrolidine hydrochloride; L-2-Methylpyrrolidine-2-methanol hydrochloride; (S)-2-Methyl-2-pyrrolidinemethanol hydrochloride; (S)-2-(Hydroxymethyl)-2-methylpyrrolidine HCl; 2-Methyl-2-pyrrolidinemethanol hydrochloride, (S)-; Pyrrolidine-2-methanol, 2-methyl-, hydrochloride, (2S)-; (2S)-2-Methyl-2-pyrrolidinemethanol hydrochloride
EINECS	Contact for details

Quality Control

Our (2S)-2-Methylpyrrolidine-2-Methanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product quality. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.