Description

(S)-(+)-Glycidyl Nosylate CAS NO 115314-14-2 is a high-value, enantiomerically pure chiral building block and electrophilic epoxide reagent. This compound is critically important for the stereoselective synthesis of complex molecules, enabling the introduction of functionalized chiral centers with high optical purity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the asymmetric synthesis of β-blockers, antiviral agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing chiral auxiliaries, catalysts, and resolving agents used in asymmetric catalysis.
• Advanced Material Monomer: Employed in the synthesis of specialty epoxy resins and polymers with tailored optical or mechanical properties.
• Organic Synthesis Reagent: Acts as a versatile electrophile in nucleophilic ring-opening reactions for installing nosylate-protected functional groups.
• Academic & Industrial Research: A valuable tool for methodological development in stereoselective synthesis and medicinal chemistry programs.

Basic Information

Product Name	(S)-(+)-Glycidyl Nosylate
CAS No.	115314-14-2
Molecular Formula	C9H9NO6S
Molecular Weight	259.24 g/mol
Synonyms	(S)-Glycidyl 4-Nitrobenzenesulfonate; (S)-(+)-Glycidyl 4-Nitrobenzenesulfonate; (S)-2-[(4-Nitrobenzenesulfonyl)oxymethyl]oxirane; (S)-Epoxypropyl Nosylate; (S)-Glycidyl p-Nosylate; (S)-Oxiran-2-ylmethyl 4-nitrobenzenesulfonate; (2S)-(-)-Glycidyl Nosylate; (S)-(+)-Glycidyl p-Nitrobenzenesulfonate
EINECS	Contact for details

Quality Control

Our (S)-(+)-Glycidyl Nosylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and purity assessment, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and chiral purity is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to light.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.