Description

Hcl-Val-Pyrrolidide CAS NO 115201-28-0 is a high-purity, protected amino acid derivative primarily used as a critical building block in advanced organic synthesis. This compound is essential for the controlled formation of peptide bonds, enabling the production of complex molecular architectures. It is a key intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Peptide Synthesis Intermediate: A fundamental building block in solid-phase and solution-phase peptide synthesis (SPPS) for constructing specific peptide sequences.
• Pharmaceutical Research & Development: Used in the R&D of novel peptide drugs, prodrugs, and bioactive compounds targeting various therapeutic areas.
• API Manufacturing: Serves as a key chiral synthon in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Bioconjugation Chemistry: Employed in the development of peptide-protein conjugates, antibody-drug conjugates (ADCs), and other bioconjugates.
• Protease Inhibitor Development: Acts as a precursor or core structure in the design and synthesis of specific protease enzyme inhibitors.
• Chemical Biology & Proteomics: Utilized as a tool compound or labeled precursor in studies of protein-protein interactions and enzymatic pathways.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) specializing in custom peptide and complex organic molecule production.

Basic Information

Product Name	Hcl-Val-Pyrrolidide
CAS No.	115201-28-0
Molecular Formula	C10H19ClN2O
Molecular Weight	218.73 g/mol
Synonyms	L-Valine pyrrolidide hydrochloride; Val-Pyrrolidide HCl; (S)-2-Amino-3-methylbutanoic acid pyrrolidide hydrochloride; 1-[(2S)-2-Amino-3-methylbutanoyl]pyrrolidine hydrochloride; Valine pyrrolidamide hydrochloride; N-[(S)-1-Amino-2-methylpropyl]-2-pyrrolidinecarboxamide hydrochloride; Pyrrolidine, 1-[(2S)-2-amino-3-methyl-1-oxobutyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our Hcl-Val-Pyrrolidide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via spectroscopic methods. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.