Description

2-Acetamido-2-Deoxy-3,4,6-Tri-o-Methyl-D-Glucose is a chemically modified derivative of N-acetylglucosamine, specifically methylated at the 3, 4, and 6 hydroxyl positions. This compound matters as a crucial high-purity building block and reference standard for advanced research and synthesis in carbohydrate chemistry. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers working on glycobiology, drug discovery, and the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex glycopeptides, glycomimetics, and nucleoside analogs for drug development.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, glycosylation pathway analysis, and glycoprotein research.
• Glycochemistry Synthesis: Acts as a protected precursor for constructing oligosaccharides, glycolipids, and other sophisticated carbohydrate structures.
• Analytical Standard: Employed in HPLC, LC-MS, and NMR for method development, calibration, and quality control of related carbohydrate-based products.
• Academic & Industrial R&D: Fundamental tool for investigating carbohydrate-protein interactions, cell surface recognition, and vaccine adjuvant development.

Basic Information

Product Name	2-Acetamido-2-Deoxy-3,4,6-Tri-o-Methyl-D-Glucose
CAS No.	115002-36-3
Molecular Formula	C11H21NO6
Molecular Weight	263.29 g/mol
Synonyms	3,4,6-Tri-O-Methyl-N-acetyl-D-glucosamine; N-Acetyl-3,4,6-tri-O-methyl-D-glucosamine; 2-Acetamido-2-deoxy-3,4,6-tri-O-methyl-D-glucopyranose; 1,3,4,6-Tetra-O-methyl-2-acetamido-2-deoxy-D-glucose; Methylated N-Acetylglucosamine; GlcNAc(3,4,6-OMe); Per-O-methylated N-acetylglucosamine derivative
EINECS	Contact for details

Quality Control

Our 2-Acetamido-2-Deoxy-3,4,6-Tri-o-Methyl-D-Glucose is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.