Description

Piperidine, 4-(2-Chloroethyl)-, Hydrochloride (1:1) is a versatile and highly functionalized piperidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the reactive chloromethyl group and the basic piperidine nitrogen, which allow for the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents. Its reliable quality and consistent supply are paramount for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, including potential central nervous system (CNS) agents, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its piperidine scaffold for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: The nitrogen atom can be utilized to create chelating ligands or functionalized catalysts for asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	Piperidine, 4-(2-Chloroethyl)-, Hydrochloride (1:1)
CAS No.	114998-54-8
Molecular Formula	C7H14ClN • HCl
Molecular Weight	184.10 g/mol
Synonyms	4-(2-Chloroethyl)piperidine hydrochloride; 1-(2-Chloroethyl)-4-piperidinol hydrochloride (tautomer); 4-(2-Chloroethyl)piperidine HCl; 4-(β-Chloroethyl)piperidine hydrochloride; N-(2-Chloroethyl)-4-piperidinol hydrochloride; 1-Piperidineethanol, 4-chloro-, hydrochloride; 4-(2-Chloroethyl)piperidinium chloride
EINECS	Contact for details

Quality Control

Our Piperidine, 4-(2-Chloroethyl)-, Hydrochloride (1:1) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.