Description

[1,1'-Binaphthalen]-2-Amine is a high-purity, chiral binaphthyl derivative that serves as a critical building block in advanced organic synthesis. Its unique axial chirality and functional amine group make it an indispensable precursor for constructing sophisticated ligands and catalysts. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it enables the development of enantioselective processes and novel functional materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and cardiovascular diseases.
• Asymmetric Catalyst & Ligand Synthesis: Core scaffold for developing novel BINOL- and BINAM-derived ligands used in asymmetric hydrogenation, cross-coupling, and other enantioselective transformations.
• Agrochemical Research: Building block for creating chiral active ingredients in herbicides, fungicides, and plant growth regulators.
• Material Science: Monomer for synthesizing chiral polymers and advanced organic frameworks (MOFs/COFs) with potential applications in sensors, optics, and separation technologies.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic chemistry and catalysis research.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals, dyes, and other high-value-added compounds requiring precise stereochemical control.

Basic Information

Product Name	[1,1'-Binaphthalen]-2-Amine
CAS No.	114858-56-9
Molecular Formula	C20H15N
Molecular Weight	269.34 g/mol
Synonyms	2-Amino-1,1'-binaphthalene; 1,1'-Binaphthalene-2-amine; BINAM; 2,2'-Diamino-1,1'-binaphthyl (Note: This is the 2,2'-isomer, a common mis-assignment); 2-Naphthyl-1-naphthylamine; (Rac)-1,1'-Binaphthalen-2-amine; 1,1'-Binaphthyl-2-amine
EINECS	Contact for details

Quality Control

Our [1,1'-Binaphthalen]-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm identity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its light-sensitive and easily oxidized nature, prolonged exposure to air and light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Racemic mixture
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.