Description

(R)-o-[(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl]-Hydroxyamine Hydrochloride is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its core value proposition lies in providing a protected, enantiomerically pure hydroxylamine derivative, enabling the stereoselective construction of complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in the development of antibiotics, antivirals, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for activity.
• Asymmetric Synthesis: Serves as a versatile reagent for introducing nitrogen and oxygen functionality in a stereocontrolled manner, useful in natural product synthesis.
• Chemical Biology & Proteomics: Can be utilized as a building block for synthesizing molecular probes or affinity tags that target specific biological pathways.
• Material Science Research: Potential intermediate for creating novel chiral ligands or catalysts used in homogeneous catalysis.
• Academic & R&D: A valuable tool for methodological development in organic chemistry laboratories focused on stereoselective reactions and heterocyclic chemistry.

Basic Information

Product Name	(R)-o-[(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl]-Hydroxyamine Hydrochloride
CAS No.	114778-50-6
Molecular Formula	C7H16ClNO3
Molecular Weight	197.66 g/mol
Synonyms	(R)-(-)-2,2-Dimethyl-4-[(hydroxyamino)methyl]-1,3-dioxolane Hydrochloride; (R)-4-(Aminoxymethyl)-2,2-dimethyl-1,3-dioxolane Hydrochloride; (R)-O-[(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl]hydroxylamine Hydrochloride; (R)-4-(Hydroxyaminomethyl)-2,2-dimethyl-1,3-dioxolane Hydrochloride; (R)-Isopropylidene Glycerol Hydroxylamine Hydrochloride; (R)-Solketal Hydroxylamine Hydrochloride; (R)-1,2-O-Isopropylidene-3-O-(hydroxyamino)propane Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-o-[(2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl]-Hydroxyamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.