Description

7-Bromo-1,2,3,4-Tetrahydro-Quinoline Hydrochloride is a versatile and high-value halogenated quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the construction of complex nitrogen-containing heterocycles, which are foundational scaffolds in modern drug discovery and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-purity building block for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in developing central nervous system (CNS) agents, kinase inhibitors, and other bioactive molecules containing the tetrahydroquinoline core.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, where the bromine atom offers a site for further functionalization.
• Organic Synthesis Reagent: A versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution, facilitating the introduction of the 7-bromotetrahydroquinoline moiety into more complex structures.
• Material Science: Employed in the research of organic semiconductors, liquid crystals, and photoactive materials due to its electron-rich aromatic system and modifiable structure.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes and tags used to study biological processes and protein functions.

Basic Information

Product Name	7-Bromo-1,2,3,4-Tetrahydro-Quinoline Hydrochloride
CAS No.	114744-51-3
Molecular Formula	C9H10BrN·HCl
Molecular Weight	248.55 g/mol (Free base: 212.09 g/mol)
Synonyms	7-Bromo-1,2,3,4-tetrahydroquinoline HCl; 7-Bromo-1,2,3,4-tetrahydroquinoline hydrochloride; 1,2,3,4-Tetrahydro-7-bromoquinoline hydrochloride; 7-Bromotetrahydroquinoline HCl; 7-Bromo-1,2,3,4-tetrahydroquinolinium chloride; 7-Bromo-3,4-dihydro-2H-quinoline hydrochloride; 7-Bromo-1,2,3,4-tetrahydroquinoline monohydrochloride
EINECS	Contact for details

Quality Control

Our 7-Bromo-1,2,3,4-Tetrahydro-Quinoline Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.