Description

5-Bromo-1,2,3,4-Tetrahydro-Quinoline Hydrochloride is a versatile brominated heterocyclic building block, primarily valued for its role as a key intermediate in advanced organic synthesis. Its molecular structure makes it particularly significant for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the tetrahydroquinoline scaffold into novel molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other functional organic materials.
• Chemical Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and in organic synthesis for constructing complex nitrogen-containing heterocycles.
• Academic & Industrial R&D: A valuable reagent for methodological development in catalysis (e.g., C-H functionalization, cross-coupling) and for exploring new chemical spaces in combinatorial chemistry.

Basic Information

Item	Details
Product Name	5-Bromo-1,2,3,4-Tetrahydro-Quinoline Hydrochloride
CAS No.	114744-50-2
Molecular Formula	C9H10BrN·HCl
Molecular Weight	248.55 g/mol
Synonyms	5-Bromo-1,2,3,4-tetrahydroquinoline HCl; 5-Bromo-1,2,3,4-tetrahydroquinoline hydrochloride; 5-Bromotetrahydroquinoline hydrochloride; 1,2,3,4-Tetrahydro-5-bromoquinoline hydrochloride; Quinoline, 5-bromo-1,2,3,4-tetrahydro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2,3,4-Tetrahydro-Quinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.