Description

2,3,4,6-Tetra-o-Benzyl-1-o-Trichloroacetimidoyl-β-D-Galactopyranose CAS NO 114743-70-3 is a sophisticated, protected galactose derivative widely used as a key glycosyl donor in stereoselective oligosaccharide synthesis. This compound is critical for constructing complex carbohydrate structures with high precision and yield, enabling the development of novel glycoconjugates. It is an essential building block for researchers and manufacturers in pharmaceutical development, particularly for creating carbohydrate-based vaccines, drug candidates, and diagnostic tools.

Application

• Glycosylation Reactions: Serves as a high-yield glycosyl donor for the stereoselective synthesis of β-linked galactosides and oligosaccharides.
• Pharmaceutical Intermediates: A critical precursor in the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and drug candidates.
• Glycoconjugate Vaccine Development: Used to build specific carbohydrate antigens for conjugate vaccine research against bacterial pathogens.
• Glycobiology Research: Enables the study of carbohydrate-protein interactions and the synthesis of defined glycan arrays for high-throughput screening.
• Diagnostic Reagent Synthesis: Employed in creating labeled glycans and probes for diagnostic assays and imaging applications.
• Chemical Biology Tool Development: Facilitates the synthesis of activity-based probes and metabolic labeling agents to study glycosylation in biological systems.

Basic Information

Product Name	2,3,4,6-Tetra-o-Benzyl-1-o-Trichloroacetimidoyl-β-D-Galactopyranose
CAS No.	114743-70-3
Molecular Formula	C36H34Cl3NO6
Molecular Weight	683.02 g/mol
Synonyms	2,3,4,6-Tetra-O-benzyl-1-O-(trichloroacetimidoyl)-β-D-galactopyranose; 2,3,4,6-Tetra-O-benzyl-α/β-D-galactopyranosyl Trichloroacetimidate; Galactosyl Trichloroacetimidate, Tetra-O-benzyl-; 1-O-(Trichloroacetimidoyl)-2,3,4,6-tetra-O-benzyl-β-D-galactopyranose; Tetra-O-benzyl-D-galactopyranosyl Trichloroacetimidate; β-D-Galactopyranose, 2,3,4,6-tetra-O-benzyl-, 1-(trichloroacetimidate); Glycosyl Donor Gal-β-TCA
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Benzyl-1-o-Trichloroacetimidoyl-β-D-Galactopyranose is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and optical rotation analysis, to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.