Description

Dl-α-Methyltryptophan Methyl Ester Hydrochloride is a synthetic tryptophan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial chiral intermediate and building block for the synthesis of complex molecules, enabling the exploration of novel therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, metabolic regulators, and other specialized bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for neurological and metabolic disorders.
• Biochemical Research: Used as a precursor or reference standard in studies involving amino acid metabolism, enzyme inhibition, and receptor binding assays.
• Peptide Synthesis: Serves as a protected or modified tryptophan analog in the solid-phase or solution-phase synthesis of specialized peptides and peptidomimetics.
• Academic & Discovery Chemistry: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Process Development: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) that incorporate modified tryptophan structures.

Basic Information

Product Name	Dl-α-Methyltryptophan Methyl Ester Hydrochloride
CAS No.	114524-80-0
Molecular Formula	C14H19ClN2O2
Molecular Weight	282.77 g/mol
Synonyms	DL-α-Methyltryptophan Methyl Ester HCl; Methyl DL-α-methyltryptophanate hydrochloride; (±)-α-Methyltryptophan methyl ester hydrochloride; α-Methyl-DL-tryptophan methyl ester hydrochloride; 3-(1H-Indol-3-yl)-2-methyl-2-aminopropanoic acid methyl ester hydrochloride; Methyl 2-amino-3-(1H-indol-3-yl)-2-methylpropanoate hydrochloride
EINECS	Contact for details

Quality Control

Our Dl-α-Methyltryptophan Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.