Description

α-(2-9)-Disialic Acid is a specific, high-purity disialylated carbohydrate derivative, a crucial building block in glycobiology research and advanced bioconjugate development. This compound matters for its role in studying and mimicking complex biological recognition processes, particularly those involving cell-surface interactions and immune system modulation. It is primarily needed by research institutions, pharmaceutical R&D teams, and diagnostic manufacturers working in areas such as vaccine development, biomarker discovery, and the synthesis of sophisticated glycoconjugates.

Application

• Glycobiology Research: A key intermediate for studying sialic acid linkages, glycan biosynthesis, and carbohydrate-protein interactions.
• Bioconjugate Synthesis: Used in the chemical and enzymatic synthesis of complex glycoproteins, glycolipids, and neoglycoconjugates for therapeutic and diagnostic applications.
• Vaccine Adjuvant & Carrier Development: Investigated for its potential immunomodulatory properties in the design of novel vaccine platforms and carbohydrate-based antigens.
• Diagnostic Reagent Production: Serves as a critical component in the development of assays and biosensors for detecting specific pathogens or biomarkers that bind to sialylated structures.
• Enzymology Studies: Employed as a substrate or inhibitor for sialyltransferases, neuraminidases (sialidases), and other glycosyl hydrolases.
• Standard Reference Material: Used as a high-purity analytical standard for HPLC, MS, or NMR in quality control and research laboratories.

Basic Information

Item	Details
Product Name	α-(2-9)-Disialic Acid
CAS No.	114474-59-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Neu5Acα2-9Neu5Ac; Disialic Acid (α2-9); 2,9-Disialic Acid; α2-9-Linked Disialic Acid; N-Acetylneuraminyl-(α2→9)-N-acetylneuraminic acid; (2→9)-Disialic Acid; Disialooligosaccharide precursor; Sialic acid dimer (α2,9)
EINECS	Contact for details

Quality Control

Our α-(2-9)-Disialic Acid is produced under stringent conditions to ensure batch-to-batch consistency and high purity suitable for research and development applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.