Description

(S)-3-Chloro-1-Phenyl-1-[2-Methyl-Phenoxyl]Propane is a chiral organic compound featuring a phenyl and an ortho-methylphenoxy group, making it a valuable chiral intermediate. Its defined stereochemistry is critical for applications requiring high enantiomeric purity, particularly in the synthesis of active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries seeking to build complex, optically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to introduce stereogenic centers.
• Agrochemical Research: Serves as a precursor in the development of chiral pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral ligands for metal-catalyzed transformations.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry research for new synthetic routes.
• Fine Chemical Production: Incorporated into the manufacture of specialty chemicals requiring specific optical purity.

Basic Information

Product Name	(S)-3-Chloro-1-Phenyl-1-[2-Methyl-Phenoxyl]Propane
CAS No.	114446-50-3
Molecular Formula	C₁₆H₁₇ClO
Molecular Weight	260.76 g/mol
Synonyms	(S)-3-Chloro-1-phenyl-1-(o-tolyloxy)propane; (S)-1-(2-Methylphenoxy)-3-chloro-1-phenylpropane; (S)-3-Chloro-1-phenyl-1-(2-methylphenoxy)propane; (S)-1-Phenyl-1-(2-methylphenoxy)-3-chloropropane; (S)-α-[(2-Methylphenoxy)methyl]benzyl chloride; (S)-3-Chloro-1-phenyl-1-(2-tolyloxy)propane; (S)-1-(o-Methylphenoxy)-3-chloro-1-phenylpropane; (S)-3-Chloro-1-phenyl-1-(ortho-methylphenoxy)propane
EINECS	Contact for details

Quality Control

Our production of (S)-3-Chloro-1-Phenyl-1-[2-Methyl-Phenoxyl]Propane adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric excess (e.e.). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We employ advanced analytical techniques, including chiral HPLC, to verify specifications, meeting the rigorous standards required for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.