Description

trans-3-Bromo-4-Hydroxytetrahydrofuran is a versatile chiral building block and halogenated heterocyclic compound of significant interest in synthetic organic chemistry. Its value lies in its functionalized tetrahydrofuran scaffold, which serves as a key intermediate for constructing complex molecules, particularly in the pharmaceutical sector. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nucleoside analogs, antiviral drugs, and other bioactive molecules.
• Chiral Synthesis: Used as a starting material or building block for the asymmetric synthesis of complex natural products and optically active compounds.
• Agrochemical Research: Serves as an intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or modifier for creating specialized polymers with unique properties.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Fine Chemical Production: Employed in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	trans-3-Bromo-4-Hydroxytetrahydrofuran
CAS No.	114429-91-3
Molecular Formula	C4H7BrO2
Molecular Weight	167.00 g/mol
Synonyms	(3R,4S)-3-Bromo-4-hydroxytetrahydrofuran; (3S,4R)-3-Bromo-4-hydroxytetrahydrofuran; 3-Bromo-4-hydroxyoxolane; trans-3-Bromo-4-hydroxyoxolane; 3-Bromotetrahydrofuran-4-ol; 3-Bromo-4-hydroxytetrahydrofuran (trans); Tetrahydro-3-bromo-4-furanol
EINECS	Contact for details

Quality Control

Our trans-3-Bromo-4-Hydroxytetrahydrofuran is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (trans)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.