Description

7-Bromo-2,3-dihydroquinolin-4(1H)-one is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core quinolinone scaffold, functionalized with a reactive bromine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed cross-coupling reactions, which are fundamental in modern synthetic chemistry.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	7-Bromo-2,3-dihydroquinolin-4(1H)-one
CAS No.	114417-34-4
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	7-Bromo-1,2,3,4-tetrahydro-4-oxoquinoline; 7-Bromo-1,2,3,4-tetrahydroquinolin-4-one; 7-Bromo-3,4-dihydro-2H-quinolin-4-one; 7-Bromo-2,3-dihydro-4(1H)-quinolinone; 4(1H)-Quinolinone, 7-bromo-2,3-dihydro-; 114417-34-4
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,3-dihydroquinolin-4(1H)-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.