Description

1,3,5-Tris(Prop-2-Ynyloxy)Benzene CAS NO 114233-80-6 is a high-purity organic building block characterized by its symmetrical benzene core functionalized with three propargyl ether groups. This compound is a critical intermediate in advanced organic synthesis, particularly valued for its ability to participate in click chemistry reactions, such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require precise molecular scaffolds for developing new active ingredients, polymers, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs) utilizing click chemistry for rapid derivatization.
• Polymer & Material Science: Acts as a trifunctional cross-linking agent or monomer for creating high-performance polymers, dendrimers, and network structures with tailored properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that require a rigid, symmetrical aromatic core.
• Ligand & Catalyst Development: Employed as a precursor for synthesizing sophisticated ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Surface Functionalization: Enables the covalent attachment of molecules to surfaces (e.g., nanoparticles, chips) via its reactive alkyne groups for sensor and diagnostic applications.
• Academic & Industrial R&D: A key reagent for exploring new synthetic methodologies and constructing complex molecular architectures in research laboratories.

Basic Information

Product Name	1,3,5-Tris(Prop-2-Ynyloxy)Benzene
CAS No.	114233-80-6
Molecular Formula	C15H12O3
Molecular Weight	240.26 g/mol
Synonyms	1,3,5-Tris(2-Propynyloxy)benzene; 1,3,5-Tris(propargyloxy)benzene; Benzene, 1,3,5-tris(2-propyn-1-yloxy)-; Tris(propargyloxy)benzene; 1,3,5-Tris(prop-2-yn-1-yloxy)benzene; Propargyl Ether of Phloroglucinol; 1,3,5-Tripropargyloxybenzene
EINECS	Contact for details

Quality Control

Our 1,3,5-Tris(Prop-2-Ynyloxy)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.