Description

Phenol, 4-[(2R,3S)-4-(1,3-Benzodioxol-5-Yl)-2,3-Dimethylbutyl]-2-Methoxy-, Rel- is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. This compound is valued for its complex molecular architecture, which incorporates a benzodioxole moiety and a chiral, substituted butyl chain attached to a methoxyphenol core. It serves as a critical building block for research and development in the pharmaceutical and agrochemical sectors, where precise stereochemistry is paramount for biological activity. Industries engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals are the primary users of this material.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the research and synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Building block for developing new crop protection agents and pesticides with specific stereochemical requirements.
• Chemical Synthesis: Versatile intermediate in advanced organic chemistry for constructing complex polycyclic or chiral molecular frameworks.
• Life Sciences R&D: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Phenol, 4-[(2R,3S)-4-(1,3-Benzodioxol-5-Yl)-2,3-Dimethylbutyl]-2-Methoxy-, Rel-
CAS No.	114127-24-1
Molecular Formula	C20H24O4
Molecular Weight	328.40 g/mol
Synonyms	Rel-4-[(2R,3S)-4-(1,3-Benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol; (rel)-(2R,3S)-1-(1,3-Benzodioxol-5-yl)-3,4-dimethyl-6-methoxy-3,4-dihydro-1H-2-benzopyran; 4-[(2R,3S)-4-(1,3-Benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol; 2-Methoxy-4-[(2R,3S)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]phenol; 1-(1,3-Benzodioxol-5-yl)-3,4-dimethyl-6-methoxy-3,4-dihydro-1H-2-benzopyran; Chiral benzodioxole phenol derivative.
EINECS	Contact for details

Quality Control

Our production of Phenol, 4-[(2R,3S)-4-(1,3-Benzodioxol-5-Yl)-2,3-Dimethylbutyl]-2-Methoxy-, Rel- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is rigorously analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP compliance for applications requiring the highest standards in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive (store away from light) and should be handled under an inert atmosphere if found to be easily oxidized. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.