Description

(1S,4S)-2-Methyl-2,5-Diazabicyclo(2.2.1)Heptane 2Hbr is a high-purity, chiral bicyclic diamine salt with significant utility in advanced organic synthesis. This compound matters as a versatile and structurally constrained building block, offering a rigid scaffold for the development of novel pharmaceuticals and chiral catalysts. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral ligands used in transition metal catalysis to induce enantioselectivity in reactions like hydrogenation and cross-coupling.
• Chemical Research & Development: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Fine Chemical Building Block: Integral for constructing complex, nitrogen-containing heterocycles and other specialty chemicals.

Basic Information

Product Name	(1S,4S)-2-Methyl-2,5-Diazabicyclo(2.2.1)Heptane 2Hbr
CAS No.	114086-15-6
Molecular Formula	C7H16N2 • 2HBr
Molecular Weight	308.04 g/mol
Synonyms	(1S,4S)-2-Methyl-2,5-diazabicyclo[2.2.1]heptane dihydrobromide; (1S,4S)-2-Methyl-2,5-diazabicyclo[2.2.1]heptane hydrobromide (2:1); 2-Methyl-2,5-diazabicyclo[2.2.1]heptane dihydrobromide, (1S,4S)-; endo-2-Methyl-2,5-diazabicyclo[2.2.1]heptane dihydrobromide; (1S,4S)-endo-2-Methyl-2,5-diazabicyclo[2.2.1]heptane 2HBr; Chiral DABCO derivative salt
EINECS	Contact for details

Quality Control

Our (1S,4S)-2-Methyl-2,5-Diazabicyclo(2.2.1)Heptane 2Hbr is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.