Description

1-Hydroxy-4-Iodonaphthalene is a high-purity iodinated naphthalene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a hydroxyl and an iodine substituent, makes it a valuable precursor for constructing complex molecules through cross-coupling and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with specific modes of action.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and photoactive materials.
• Cross-Coupling Reactions: Essential reagent in Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Fluorescent Probe Synthesis: Intermediate for creating iodinated fluorescent dyes and molecular probes for bioimaging.

Basic Information

Product Name	1-Hydroxy-4-Iodonaphthalene
CAS No.	113855-57-5
Molecular Formula	C₁₀H₇IO
Molecular Weight	270.07 g/mol
Synonyms	4-Iodo-1-naphthol; 1-Naphthol, 4-iodo-; 4-Iodonaphthalen-1-ol; 1-Hydroxy-4-iodonaphthalene; Naphthalen-1-ol, 4-iodo-; 4-Iodo-1-hydroxynaphthalene; 1-Naphthalenol, 4-iodo-
EINECS	Contact for details

Quality Control

Every batch of 1-Hydroxy-4-Iodonaphthalene is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.