Description

1-Iodoethynyl-2-Nitrobenzene is a specialized aromatic building block featuring both an iodoethynyl and a nitro functional group. This unique bifunctional structure makes it a valuable intermediate for constructing complex molecules in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in cross-coupling reactions and the synthesis of novel active compounds.

Application

• Key intermediate in Sonogashira cross-coupling reactions for carbon-carbon bond formation.
• Building block for the synthesis of pharmaceutical candidates, particularly those requiring functionalized aromatic scaffolds.
• Precursor in the development of agrochemicals and specialty fine chemicals.
• Used in material science research for creating novel organic electronic materials or ligands.
• Intermediate for the preparation of biologically active molecules in medicinal chemistry programs.
• Starting material for synthesizing complex nitro- and iodine-substituted aromatic compounds.

Basic Information

Product Name	1-Iodoethynyl-2-Nitrobenzene
CAS No.	113783-27-0
Molecular Formula	C8H4INO2
Molecular Weight	272.03 g/mol
Synonyms	2-Nitro-1-(iodoethynyl)benzene; 1-Ethynyl-2-nitrobenzene, 1-iodo-; (2-Nitrophenyl)iodoacetylene; 1-Iodo-2-nitroethynylbenzene; o-Nitrophenyl iodoacetylene; 2-Nitrophenyl(iodo)acetylene
EINECS	Contact for details

Quality Control

Our 1-Iodoethynyl-2-Nitrobenzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.