Description

n-tert-Butyl-(2-Sulfophenyl)Nitrone is a specialized nitrone spin trap compound, widely recognized for its efficacy in electron paramagnetic resonance (EPR) spectroscopy. Its primary value lies in its ability to effectively capture and stabilize short-lived free radicals, enabling their detection and characterization in complex chemical and biological systems. This makes it an essential research-grade chemical for scientists and R&D professionals in the fields of polymer chemistry, material science, pharmaceutical development, and mechanistic biochemistry, where understanding radical-mediated processes is critical.

Application

• Free Radical Research & Detection: As a highly effective spin trap for identifying and studying transient free radicals in chemical reactions and biological systems using EPR spectroscopy.
• Polymer Science & Material Development: Used to investigate radical initiation, propagation, and termination mechanisms in polymerization processes and to study the degradation of polymers and advanced materials.
• Pharmaceutical & Biomedical Research: Employed to detect and quantify reactive oxygen species (ROS) and other radicals in cellular models, aiding in the study of oxidative stress, disease mechanisms, and drug efficacy.
• Antioxidant Activity Assessment: Serves as a key reagent in assays designed to evaluate the radical-scavenging capacity and antioxidant potential of natural products, food additives, and cosmetic ingredients.
• Industrial Chemistry & Catalysis: Applied in mechanistic studies of catalytic cycles and industrial chemical processes where radical intermediates play a pivotal role.

Basic Information

Product Name	n-tert-Butyl-(2-Sulfophenyl)Nitrone
CAS No.	113443-50-8
Molecular Formula	C11H15NO3S
Molecular Weight	241.31 g/mol
Synonyms	2-Sulfo-N-tert-butylphenylnitrone; S-PBN; 2-Sulfophenyl-N-tert-butylnitrone; N-tert-Butyl-α-(2-sulfophenyl)nitrone; tert-Butyl(2-sulfophenyl)nitrone; Nitrone Spin Trap S-PBN; 2-Sulfobenzaldehyde N-tert-butylnitrone; Free Radical Trap S-PBN
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-(2-Sulfophenyl)Nitrone is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, essential for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.