Description

2,2-Dimethyl-4(S)-4-Bromomethyl-1,3-Dioxalane is a high-value chiral building block and brominated acetal derivative. This compound matters for its role as a key intermediate in the synthesis of complex pharmaceutical molecules and fine chemicals, where its stereochemistry and reactive bromomethyl group enable precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for creating active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular drug candidates.
• Asymmetric Synthesis: Used in stereoselective reactions to introduce chiral centers into target molecules with high enantiomeric purity.
• Nucleoside Analogue Preparation: Serves as a protected, functionalized precursor in the development of modified nucleosides for therapeutic applications.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialized polymers with tailored properties.
• Agrochemical Synthesis: Employed in the research and development of chiral pesticides and herbicides.
• Material Science Research: Utilized in creating novel organic frameworks and advanced materials with specific optical or electronic characteristics.

Basic Information

Product Name	2,2-Dimethyl-4(S)-4-Bromomethyl-1,3-Dioxalane
CAS No.	113428-57-2
Molecular Formula	C6H11BrO2
Molecular Weight	195.06 g/mol
Synonyms	(4S)-4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane; 4(S)-Bromomethyl-2,2-dimethyl-1,3-dioxolane; (S)-4-Bromomethyl-2,2-dimethyl-1,3-dioxolane; 2,2-Dimethyl-4(S)-(bromomethyl)-1,3-dioxolane; (S)-2,2-Dimethyl-4-bromomethyl-1,3-dioxolane; (S)-(-)-4-Bromomethyl-2,2-dimethyl-1,3-dioxolane; Bromomethyl dioxolane derivative
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-4(S)-4-Bromomethyl-1,3-Dioxalane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.