Description

4-Chloro-3-(trifluoromethoxy)nitrobenzene is a high-purity, multi-functional aromatic intermediate of significant commercial importance. Its unique molecular structure, featuring chloro, nitro, and trifluoromethoxy substituents, makes it a versatile building block for synthesizing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for the development of advanced active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethoxy and nitro groups.
• Pharmaceutical Synthesis: Serves as a critical building block for creating pharmacologically active compounds, particularly in medicinal chemistry research and development.
• Material Science Research: Used in the development of specialty chemicals, liquid crystals, and advanced polymers due to its distinct electronic properties.
• Dye and Pigment Intermediate: Functions as a starting material for synthesizing complex dyes and organic pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki-Miyaura coupling to create more complex biaryl structures.

Basic Information

Product Name	4-Chloro-3-(trifluoromethoxy)nitrobenzene
CAS No.	113421-97-9
Molecular Formula	C7H3ClF3NO3
Molecular Weight	241.55 g/mol
Synonyms	1-Chloro-4-nitro-2-(trifluoromethoxy)benzene; 4-Chloro-3-(trifluoromethoxy)-1-nitrobenzene; 2-(Trifluoromethoxy)-4-chloronitrobenzene; 4-Chloro-α,α,α-trifluoro-3-nitroanisole; 4-Chloro-3-nitro-α,α,α-trifluoroanisole; Benzene, 1-chloro-4-nitro-2-(trifluoromethoxy)-; 4-Chloro-3-(trifluoromethoxy)nitrobenzene
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(trifluoromethoxy)nitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by FT-IR and NMR, and quantification of key impurities. A Certificate of Analysis (COA) detailing all specifications is available with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.