Description

6-Amino-8-Fluoro-3,4-Dihydroquinolin-2(1H)-One is a high-purity fluorinated quinolinone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for synthesizing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel fluorinated drug candidates, especially in oncology and CNS research.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development of new APIs requiring the 3,4-dihydroquinolin-2(1H)-one core structure.
• Chemical Synthesis Research: Serves as a versatile precursor in organic synthesis for creating complex heterocyclic compounds in academic and industrial R&D labs.
• Agrochemical Research: Potential intermediate in the development of new fluorinated agrochemicals, such as herbicides or pesticides, leveraging its bioactive quinolinone structure.

Basic Information

Product Name	6-Amino-8-Fluoro-3,4-Dihydroquinolin-2(1H)-One
CAS No.	113225-70-0
Molecular Formula	C9H9FN2O
Molecular Weight	180.18 g/mol
Synonyms	8-Fluoro-6-amino-3,4-dihydro-2(1H)-quinolinone; 6-Amino-8-fluoro-1,2,3,4-tetrahydroquinolin-2-one; 8-Fluoro-6-amino-1,2,3,4-tetrahydroquinolin-2-one; 6-Amino-8-fluoro-3,4-dihydro-1H-quinolin-2-one; 6-Amino-8-fluoro-1,2,3,4-tetrahydro-2-quinolinone; 113225-70-0; 8-Fluoro-6-amino-3,4-dihydroquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 6-Amino-8-Fluoro-3,4-Dihydroquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.