Description

Hydroquinidine 4-Chlorobenzoate is a high-purity, specialized alkaloid derivative used as a chiral catalyst and resolving agent. This compound is valued for its ability to induce and control stereoselectivity in asymmetric synthesis, a critical process for producing enantiomerically pure pharmaceuticals and fine chemicals. It is an essential tool for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients with high optical purity.

Application

• Asymmetric Synthesis Catalyst: Employed as a chiral ligand or catalyst in enantioselective reactions, such as asymmetric dihydroxylation or phase-transfer catalysis.
• Chiral Resolution Agent: Used to separate racemic mixtures of carboxylic acids or other acidic compounds via diastereomeric salt formation.
• Pharmaceutical Intermediate: Serves as a key building block or resolving agent in the synthesis of optically active drug substances and active pharmaceutical ingredients (APIs).
• Research & Development: A critical reagent in academic and industrial laboratories for method development and exploring new chiral transformations.
• Fine Chemical Production: Applied in the manufacture of specialty chemicals where control of molecular handedness is required for functionality.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in regulated environments.

Basic Information

Product Name	Hydroquinidine 4-Chlorobenzoate
CAS No.	113162-02-0
Molecular Formula	C25H28ClN2O3
Molecular Weight	439.96 g/mol
Synonyms	Hydroquinidine 4-chlorobenzoate; (8S,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol 4-chlorobenzoate; 4-Chlorobenzoic acid (8α,9R)-10,11-dihydro-6'-methoxycinchonan-9-yl ester; Dihydroquinidine 4-chlorobenzoate; Hydroquinidine p-chlorobenzoate; Quinidine derivative 4-chlorobenzoate; (9R)-Hydroquinidine 4-chlorobenzoate
EINECS	Contact for details

Quality Control

Our Hydroquinidine 4-Chlorobenzoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and identification of key impurities, to ensure it meets the stringent requirements for chiral auxiliary and catalyst applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.