Description

Ethyl 6,7-Difluoro-1-Methyl-4-Oxo-4H-[1,3]Thiazeto[3,2-A]Quinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 113046-72-3. This compound is a critical building block in the synthesis of novel fluoroquinolone-based antibacterial agents, offering significant value in modern drug discovery. It is primarily required by research institutions and pharmaceutical manufacturers engaged in developing next-generation antibiotics and other therapeutic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of new-generation fluoroquinolone antibiotics.
• Antibacterial Research: Used in R&D for developing compounds with activity against resistant bacterial strains.
• Organic Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal chemistry.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in API manufacturing.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) of quinolone derivatives.

Basic Information

Product Name	Ethyl 6,7-Difluoro-1-Methyl-4-Oxo-4H-[1,3]Thiazeto[3,2-A]Quinoline-3-Carboxylate
CAS No.	113046-72-3
Molecular Formula	C₁₅H₁₂F₂N₂O₃S
Molecular Weight	338.33 g/mol
Synonyms	6,7-Difluoro-1-methyl-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid ethyl ester; Ethyl 6,7-difluoro-1-methyl-4-oxo-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate; 113046-72-3; Thiazetoquinoline carboxylate derivative; Fluoroquinolone intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 6,7-Difluoro-1-Methyl-4-Oxo-4H-[1,3]Thiazeto[3,2-A]Quinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.