Description

D-Glucosamine-2,3-Disulfate, Disodium Salt is a highly sulfated derivative of the amino sugar glucosamine, characterized by its disulfate groups at the 2 and 3 positions. This specific chemical modification is critical for enhancing biological activity, particularly in modulating enzyme interactions and cellular signaling pathways. It is primarily sought by research institutions and pharmaceutical developers for applications in biochemical research, drug discovery, and as a reference standard for analytical studies.

Application

• Biochemical Research: Used as a key intermediate or substrate in enzymatic studies, particularly those involving sulfatases and glycosaminoglycan (GAG) metabolism.
• Pharmaceutical Development: Serves as a reference standard or a building block in the R&D of novel therapeutic agents targeting inflammation, osteoarthritis, and cartilage repair.
• Glycosaminoglycan (GAG) Mimetics: Acts as a precursor or model compound for synthesizing heparin/heparan sulfate analogs to study their anticoagulant and cell-signaling properties.
• Analytical Chemistry: Employed as a high-purity calibration standard in HPLC, LC-MS, and other chromatographic methods for quantitative analysis.
• Cell Culture & In Vitro Studies: Utilized in media supplements or as an additive to investigate its effects on chondrocyte metabolism and extracellular matrix synthesis.

Basic Information

Product Name	D-Glucosamine-2,3-Disulfate, Disodium Salt
CAS No.	112898-34-7
Molecular Formula	C6H11NO11S2Na2
Molecular Weight	407.23 g/mol
Synonyms	Disodium D-Glucosamine-2,3-Disulfate; Glucosamine 2,3-Disulfate Disodium Salt; 2,3-Di-O-sulfo-D-glucosamine Disodium Salt; D-Glucosamine, 2,3-bis(hydrogen sulfate), disodium salt; Chondrosulf; GlcN-2,3-S Disodium Salt; Amino-2-deoxy-2,3-di-O-sulfo-D-glucopyranose Disodium Salt
EINECS	Contact for details

Quality Control

Our D-Glucosamine-2,3-Disulfate, Disodium Salt is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), residual solvents, and sulfate content is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider using inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Sulfate Content	Conforms to theoretical value
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.