Description

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. Its core value lies in its role as a critical building block in the synthesis of modern fluoroquinolone antibiotics, enabling the development of potent antimicrobial agents. This compound is essential for research institutions and manufacturers in the pharmaceutical and fine chemical sectors focused on active pharmaceutical ingredient (API) development and production.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a crucial precursor in the synthesis of next-generation antibacterial agents.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry for the discovery and optimization of novel quinolone-based therapeutic compounds.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in scaled-up production processes for final antibiotic APIs.
• Chemical Synthesis Studies: Utilized in academic and industrial labs to study structure-activity relationships (SAR) within the quinolone class.
• Process Chemistry Development: Acts as a standard for developing and validating efficient, high-yield synthetic routes.

Basic Information

Product Name	1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester
CAS No.	112811-71-9
Molecular Formula	C₁₆H₁₅F₂NO₄
Molecular Weight	323.29 g/mol
Synonyms	Ethyl 1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 6,7-Difluoro-1-cyclopropyl-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester; Quinolone Carboxylic Acid Ester Intermediate; Fluoroquinolone Intermediate Ester; CP-99,219 Ethyl Ester (Key Intermediate for Trovafloxacin)
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity suitable for pharmaceutical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.