Description

4-Bromo-2-Fluorobenzylamine is a versatile halogenated benzylamine building block of significant importance in advanced organic synthesis. Its bifunctional nature, featuring both a reactive amine group and halogen substituents, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials where its aromatic core and functional groups modify material properties.
• Chemical Biology & Proteomics: Useful as a linker or tagging reagent in bioconjugation and probe development for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse R&D projects.

Basic Information

Product Name	4-Bromo-2-Fluorobenzylamine
CAS No.	112734-22-2
Molecular Formula	C7H7BrFN
Molecular Weight	204.04 g/mol
Synonyms	(4-Bromo-2-fluorophenyl)methanamine; 1-(Aminomethyl)-4-bromo-2-fluorobenzene; 2-Fluoro-4-bromobenzylamine; Benzenemethanamine, 4-bromo-2-fluoro-; 4-Bromo-2-fluoro-benzenemethanamine; 4-Bromo-2-fluorobenzyl amine; α-Amino-4-bromo-2-fluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.