Description

n-Methyl-n-(1-Acetoxy-2-Oxopropyl)Nitrosamine is a specialized nitrosamine compound with the CAS registry number 112725-15-2. This chemical is of significant interest in advanced organic synthesis and research, particularly as a precursor or model compound in the study of nitrosation reactions and related chemical pathways. It is primarily utilized by research institutions, pharmaceutical development laboratories, and specialty chemical manufacturers engaged in synthetic chemistry and analytical method development.

Application

• Research & Development: Serves as a critical reference standard or intermediate in academic and industrial R&D for studying nitrosamine chemistry and reactivity.
• Pharmaceutical Analysis: Used as an analytical standard in method development and validation for the detection and quantification of nitrosamine impurities (NDSRIs) in active pharmaceutical ingredients (APIs) and drug products.
• Chemical Synthesis: Acts as a specialized building block or precursor in the synthesis of complex organic molecules for research purposes.
• Toxicology Studies: Employed in metabolic and toxicological research to understand the formation, fate, and biological impact of nitrosamine compounds.
• Quality Control Laboratories: Provides a known compound for calibrating analytical equipment like HPLC-MS/GC-MS in pharmaceutical and chemical QC environments.
• Regulatory Compliance Testing: Supports compliance efforts with global health authority guidelines (e.g., FDA, EMA) concerning nitrosamine risk assessment in pharmaceuticals.

Basic Information

Product Name	n-Methyl-n-(1-Acetoxy-2-Oxopropyl)Nitrosamine
CAS No.	112725-15-2
Molecular Formula	C7H12N2O4
Molecular Weight	188.18 g/mol
Synonyms	N-Methyl-N-(1-acetoxy-2-oxopropyl)nitrosamine; N-Nitroso-N-methyl-3-oxobutyl acetate; 1-(Acetoxy)-2-propanone, N-methyl-N-nitroso-; N-Methyl-N-nitroso-3-oxobutyl acetate; N-Methyl-N-(3-oxobutyl)nitrosamine acetate; Acetic acid 1-(methylnitrosoamino)-3-oxobutyl ester; 112725-15-2
EINECS	Contact for details

Quality Control

Every batch of n-Methyl-n-(1-Acetoxy-2-Oxopropyl)Nitrosamine is produced and analyzed under strict quality management protocols. We provide comprehensive analytical data to support its use as a high-purity reference material. A detailed Certificate of Analysis (COA), including results from HPLC, GC-MS, and NMR analyses for identity, purity, and impurity profile, is supplied with each shipment to ensure traceability and meet the stringent requirements of research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.