Description

(1S,4R)-2-Azabicyclo[2.2.1]Heptane Hydrochloride is a high-purity, chiral bicyclic amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its rigid, constrained structure makes it a valuable scaffold for constructing complex molecules with specific three-dimensional properties. This compound is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis Ligand: Used to develop novel chiral ligands and organocatalysts for enantioselective synthesis.
• Agrochemical Synthesis: Employed in the research and development of advanced, stereospecific pesticides and herbicides.
• Chemical Biology Probe: Serves as a core structure for designing molecular probes to study enzyme function and receptor binding.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique structural and optical properties.

Basic Information

Product Name	(1S,4R)-2-Azabicyclo[2.2.1]Heptane Hydrochloride
CAS No.	112458-38-5
Molecular Formula	C6H12ClN
Molecular Weight	133.62 g/mol
Synonyms	(1S,4R)-(-)-2-Azabicyclo[2.2.1]heptane hydrochloride; endo-(-)-2-Azabicyclo[2.2.1]heptane hydrochloride; (1S,4R)-2-Azanorbornane hydrochloride; (-)-2-Azabicyclo[2.2.1]heptane hydrochloride; (1S,4R)-Bicyclo[2.2.1]heptan-2-amine hydrochloride; 2-Azanorbornane hydrochloride, (1S,4R)-(-)-; endo-2-Azabicyclo[2.2.1]heptane HCl
EINECS	Contact for details

Quality Control

Our (1S,4R)-2-Azabicyclo[2.2.1]Heptane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.