Description

2-Fluoro-1,1-Dimethyl-Ethylamine Hcl-Salt is a high-purity, fluorinated amine salt building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical precursor for introducing the unique steric and electronic properties of the 1,1-dimethyl-2-fluoroethylamine moiety into target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom can enhance bioavailability and stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptide Mimetics and Modifications: Facilitates the incorporation of fluorinated amine structures into peptides to alter their conformational stability and metabolic profile.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced materials with tailored surface properties.
• Chemical Biology Probes: Useful for creating fluorinated probes and tags to study biological processes and protein interactions.

Basic Information

Product Name	2-Fluoro-1,1-Dimethyl-Ethylamine Hcl-Salt
CAS No.	112433-51-9
Molecular Formula	C4H11ClFN
Molecular Weight	127.59 g/mol
Synonyms	1,1-Dimethyl-2-fluoroethylamine hydrochloride; 2-Fluoro-1,1-dimethylethylamine hydrochloride; 2-Fluoro-N,N-dimethyl-ethanaminium chloride; (2-Fluoro-1,1-dimethylethyl)amine hydrochloride; 1-Amino-2-fluoro-2-methylpropane hydrochloride; α-Fluoro-tert-butylamine hydrochloride; tert-Butyl(fluoro)amine hydrochloride; 2-Fluoro-tert-butylamine HCl
EINECS	Contact for details

Quality Control

Our 2-Fluoro-1,1-Dimethyl-Ethylamine Hcl-Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity building blocks under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.