Description

Spiro6,8-Dioxabicyclo3.2.1Octane-4,2-Oxirane, 2-(Phenylmethoxy)-, 1R-(1.Alpha.,2.Alpha.,4.Beta.,5.Alpha.)- is a high-purity, stereochemically defined spirocyclic oxirane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique fused bicyclic structure with an epoxide functional group makes it invaluable for constructing complex molecular architectures with precise stereocontrol. This compound is primarily sought after by pharmaceutical R&D and fine chemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and catalysts for enantioselective transformations.
• Advanced Material Synthesis: Building block for specialty polymers and functional materials requiring rigid, stereodefined backbones.
• Agrochemical Research: Intermediate in the development of new generation, stereospecific pesticides and herbicides.
• Academic & Institutional Research: Used in methodological studies and the exploration of new spirocyclic and epoxide chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-fidelity chiral epoxides.

Basic Information

Product Name	Spiro6,8-Dioxabicyclo3.2.1Octane-4,2-Oxirane, 2-(Phenylmethoxy)-, 1R-(1.Alpha.,2.Alpha.,4.Beta.,5.Alpha.)-
CAS No.	112356-61-3
Molecular Formula	C13H14O4
Molecular Weight	234.25 g/mol
Synonyms	1R-(1α,2α,4β,5α)-2-(Benzyloxy)spiro[6,8-dioxabicyclo[3.2.1]octane-4,2'-oxirane]; (1R,2R,4S,5R)-2-(Benzyloxy)-1,6-dioxaspiro[2.4]heptane-4,2'-oxirane; Spiro[6,8-dioxabicyclo[3.2.1]octane-4,2'-oxirane], 2-(phenylmethoxy)-, (1R,1α,2α,4β,5α)-; Benzyl 2,3-anhydro-4,6-O-benzylidene-α-D-mannopyranoside derivative; Chiral spirocyclic epoxide; 2-(Benzyloxy)spiro[6,8-dioxabicyclo[3.2.1]octane-4,2'-oxirane] (1R,1α,2α,4β,5α)-isomer
EINECS	Contact for details

Quality Control

Our Spiro6,8-Dioxabicyclo3.2.1Octane-4,2-Oxirane, 2-(Phenylmethoxy)-, 1R-(1.Alpha.,2.Alpha.,4.Beta.,5.Alpha.)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practice (cGMP) principles where applicable. Our products undergo rigorous quality testing, including chiral purity verification, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to preserve epoxide integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.